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Publications

Structural basis of human 20S proteasome biogenesis.

Zhang H, Zhou C, Mohammad Z, Zhao J.

bioRxiv (2024 August); doi: https://doi.org/10.1101/2024.08.08.607236

Structural insights into the human PA28–20S proteasome enabled by efficient tagging and purification of endogenous proteins

Zhao J*^, Makhija S*, Zhou C, Zhang H, Wang Y, Muralidharan M, Huang B^, Cheng Y^.

Proceedings of the National Academy of Sciences of the United States of America (2022 July); 119(33): e2207200119.

*Equal contribution, ^Co-corresponding author

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. 

Gordon D, et al *. Science (2020 December) 370; 6521: 1-25. 

*As part of the Quantitative Biosciences Institute Coronavirus Research Group 

Irritant-evoked activation and calcium modulation of the TRPA1 receptor. 

Zhao J*, King JL*, Paulsen CE, Cheng Y, Julius D. Nature (2020 September); 585: 141-5. 

*Equal contribution 

Amino and PEG-amino graphene oxide grids enrich and protect samples for high-resolution single particle cryo-electron microscopy. 

Wang F, Yu Z, Betegon M, Campbell MG, Aksel T, Zhao J, Li S, Douglas SM, Cheng Y, Agard DA. Journal of Structural Biology (2020 February); 209(2). 

The first single particle analysis Map Challenge: A summary of the assessments. 

Heymann JB, Marabini R, Kazemi M, Sorzano COS, Holmdahl M, Mendez JH, Stagg SM, Jonic S, Palovcak E, Armache JP, Zhao J, Cheng Y, Pintilie G, Chiu W, Patwardhan A, Carazo JM. Journal of Structural Biology (2018 November); 204(2): 291-300. 

Cryo-EM structures of the TMEM16A calcium-activated chloride channel. 

Dang S, Feng S, Tien J, Peters C, Bulkley D, Lolicato M, Zhao J, Zuberbuhler K, Ye W, Qi T, Craik CS, Jan YN, Minor Jr DL, Cheng Y, Jan LY. Nature (2017 December 21); 552:426-29. 

Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. 

Zhao J, Beyrakhova K, Liu Y, Alvarez CP, Bueler SA, Xu L, Xu C, Boniecki MT, Kanelis, V, Luo ZQ, Cygler M, Rubinstein JL. PLoS Pathogens (2017 June 1); 13(6): e1006394. https://doi.org/10.1371/journal.ppat.1006394 

Molecular dynamics-based refinement and validation with Resolution Exchange MDFF for sub-5 A cryo-electron microscopy maps. 

Singharoy A, Teo I, McGreevy R, Stone JE, Zhao J, Schulten K. eLife (2016 July 7); 10.7554/eLife.16105. 

Models of the a subunits of the T. thermophilus V/A-ATPase and the S. cerevisiae V-ATPase by cryo-EM and evolutionary covariance. 

Schep D, Zhao J, Rubinstein JL. Proceedings of the National Academy of Sciences of the United States of America (2016 Mar 22); 113(12):3245-50. 

Description and comparison of algorithms for correcting anisotropic magnification in cryo-EM images. 

Zhao J, Brubaker MA, Benlekbir S, Rubinstein JL. Journal of Structural Biology (2015 Nov 1); 192(2):209-215. 

Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. 

Zhao J*, Benlekbir S*, Rubinstein JL. Nature (2015 May 14); 521: 241-5. 

*Equal contribution 

TMaCS: a hybrid template matching and classification system for partially-automated particle selection. 

Zhao J, Brubaker MA, Rubinstein JL. Journal of Structural Biology (2013 Mar 1); 181(3):234-42. 

The study of vacuolar-type ATPases by single particle electron microscopy. 

Zhao J, Rubinstein JL. Biochemistry and Cell Biology (2014 Dec); 92(6): 460-6. Review. 

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